Welcome to Middletown Connecticut. Middletown is located in Middlesex County along the Connecticut River, and is a diverse, vibrant community with a rich history and a dynamic cultural scene. The city is home to Wesleyan University, which contributes to its lively atmosphere with a variety of cultural and educational events that are open to the public. Middletown's downtown area is known for its array of restaurants, cafes, and boutiques, along with a growing arts scene that includes galleries and performance spaces. The city also offers numerous parks and nature trails, providing residents and visitors with ample opportunities for outdoor activities.